Thus, Circle administrators and inCytes content team can define which server will be set as a default for storing Patient’s PI data, including all answers to PI questions, once an investigator is creating a new case for the particular Circle. At the moment, you can select the following options/servers for the Circle:

➢   USA
➢   CA (Canada)
➢   Investigator’s (matches the investigator’s setting)

To define the PI server for the Circle:

1. Navigate to Circles and select the required one from the list

2. Click EDIT‍

3. At the bottom of the Edit Circle modal, select the required Patients' PI Data Storage

4. To restrict Circle members to change the server for another one, switch on the toggle Required.

➢   Self-enrolled patient registered in the Circle with ‘Investigator’s PI Data Storage’ has the Circle founder’s PI Region.
➢   Self-enrolled patient registered in the Circle with defined PI Region Storage stores data on the corresponding region.
➢   Already registered patients store the data independent of the Circle settings.